Driving to Château de Chambord is easy from most parts of the Loire Valley. The chateau is off minor country roads not far from Blois. Visits to Chambord thus combine easily with seeing the chateaux at Blois, Cheverny, and Chaumont.
The closest highway exit is Blois on Autoroute A10 from Paris via Orléans to Tours.
Distances to Château de Chambord from other cities are around: